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Funding basic science to advance cancer research: Cancerfonden distributes 28 million SEK to Lund Stem Cell Center researchers

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 20 December 2022 Earlier this fall, the Swedish Cancer Foundation (Cancerfonden) distributed 133 million SEK to 41 cancer researchers at Lund University. Nearly a quarter of this - 28 million SEK - has been awarded to 11 researchers from Lund Stem Cell Center, funding translational research which seeks to advance cance

https://www.stemcellcenter.lu.se/article/funding-basic-science-advance-cancer-research-cancerfonden-distributes-28-million-sek-lund-stem-cell - 2025-02-21

Toward a personalized approach to the study and treatment of bone cancers

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 21 December 2022 Immunofluorescence image of lab generated human ossicles or mini bones. Image credit: Dr. Dimitra Zacharaki Researchers at Lund University and Lund Stem Cell Center have generated human mini bones in the lab which mirror the composition and function of human bone. The results published in Science Trans

https://www.stemcellcenter.lu.se/article/toward-personalized-approach-study-and-treatment-bone-cancers - 2025-02-21

Reprogramming cancer cells to impair glioblastoma growth

Published 17 January 2023 Control (right) and treated (left). Image credit: Francesco Trovato. Lund Stem Cell Center researchers from Lund University and Skåne University Hospital have uncovered a way to impair the growth and progression of glioblastoma tumor cells - the most aggressive form of brain cancer. The study, published in Molecular Cancer Therapeutics, shows it is possible to transform t

https://www.stemcellcenter.lu.se/article/reprogramming-cancer-cells-impair-glioblastoma-growth - 2025-02-21

ERC grant supports new innovative advancements in immunotherapy research

By press [at] med [dot] lu [dot] se (The Faculty of Medicine) - published 26 January 2023 Principal Investigator, Filipe Pereira. Photo: Kennet Ruona. Professor Filipe Pereira, researcher at the Lund Stem Cell Center, is the principal investigator of one of two innovation-driven research initiatives at Lund University to receive a Proof of Concept Grant from the European Research Council (ERC). Th

https://www.stemcellcenter.lu.se/article/erc-grant-supports-new-innovative-advancements-immunotherapy-research - 2025-02-21

Unveiling the Gender Gap in Immunity: Camila Consiglio joins the Lund Stem Cell Center

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 1 February 2023 While it is well known that men and women have different health needs, have you ever considered why? The Systems Immunology research group, led by Camila Consiglio, has. Together, Lund Stem Cell Center’s newest members are working to uncover whether the answer lies in the differences between the female

https://www.stemcellcenter.lu.se/article/unveiling-gender-gap-immunity-camila-consiglio-joins-lund-stem-cell-center - 2025-02-21

Bioengineering and Cell-derived Strategies for Salivary Gland Regeneration: a Ph.D. Interview with Jiao Dong

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 20 February 2023 Jiao Dong defended her Ph.D. thesis on the 8th of February 2023. Inspired by the memory of patients she met during her time as a student studying oral surgery in China, she has spent the past four years researching a regenerative medicine strategy that can be used to repair the function of the salivary

https://www.stemcellcenter.lu.se/article/bioengineering-and-cell-derived-strategies-salivary-gland-regeneration-phd-interview-jiao-dong - 2025-02-21

Generating human astrocytes for disease modeling: a Ph.D. Interview with Ella Quist

Published 22 February 2023 Last month, Ella Quist defended her Ph.D. thesis. After beginning her research journey as a master’s student within our Ph.D. Preparatory Program, she dedicated the last several years to developing more efficient methods that can be used to generate functional and mature astrocytes for disease modeling of neurological disorders. In this interview, we learn more about her

https://www.stemcellcenter.lu.se/article/generating-human-astrocytes-disease-modeling-phd-interview-ella-quist - 2025-02-21

New insights into fetal development may protect against leukaemia

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 23 February 2023 Bildkälla: iStock/Pedre During the fetal stage, a number of so-called cell programs run that are vital to the development of the fetus. In a study published in Cell Reports, researchers from Lund Stem Cell Center at Lund University demonstrate that one of these fetal programs appears to protect against acute m

https://www.stemcellcenter.lu.se/article/new-insights-fetal-development-may-protect-against-leukaemia - 2025-02-21

Exploring the role of YAP and TAZ in the lung epithelium: a Ph.D. Interview with Hani Alsafadi

Published 27 February 2023 Hani Alsafadi defended his Ph.D. thesis on the 13th of February, 2023. With a longstanding interest in biomedical research and a passion for better understanding one of the least regenerative organs in the body, the lung, he has spent the past four years helping to uncover some of the mechanisms that may drive a lung disease currently without a cure, idiopathic pulmonary

https://www.stemcellcenter.lu.se/article/exploring-role-yap-and-taz-lung-epithelium-phd-interview-hani-alsafadi - 2025-02-21

Shining the spotlight on rare disease research

Published 28 February 2023 ​​​​​​​Did you know that about 70% of rare diseases begin in childhood? How about that 1 in 5 cancers are considered a rare disease? Or that nearly three-quarters of all rare diseases are genetic diseases? With more than 6,000 rare diseases known to impact the lives of an estimated 300 million people around the world – rare diseases are all too common. Limited knowledge

https://www.stemcellcenter.lu.se/article/shining-spotlight-rare-disease-research - 2025-02-21

First patient receives milestone stem cell-based transplant for Parkinson’s Disease

By press [at] med [dot] lu [dot] se (Tove Smeds) - published 1 March 2023 On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed by Lund Stem Cell Center researchers at Lund University and it is now being tested in patients for the first time. The transplantation product i

https://www.stemcellcenter.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease - 2025-02-21

New methods for phenotypic antibody discovery: a Ph.D. Interview with Jenny Mattsson

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 6 March 2023 On 03 March 2023, Jenny Mattsson defended her Ph.D. thesis. With the goal to broaden the availability of antibody-based drugs for patients with cancer and other diseases, she has spent the past several years working to develop new methods that can be used to identify new antibodies and antibody targets. In

https://www.stemcellcenter.lu.se/article/new-methods-phenotypic-antibody-discovery-phd-interview-jenny-mattsson - 2025-02-21

Inspiring tomorrow's scientists: Students explore the world of stem cells on UniStem Day 2023

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 21 March 2023 Highschool students learn how the extraordinary regenerative powers of salamanders can help us discover new ways to fight diseases in humans in a UniStem Day 2023 workshop led by researchers in the Leigh Group. Have you ever wondered what it takes to grow a brain in a petri dish or how scientists use viru

https://www.stemcellcenter.lu.se/article/inspiring-tomorrows-scientists - 2025-02-21

Eggs can help us understand neuroblastoma

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 29 March 2023 Sofie Mohlin's research focuses on neuroblastoma. Photo: Åsa Hansdotter. There is a large carton of chicken eggs on the bench in Sofie Mohlin's laboratory. They have been delivered during the morning and soon they will be placed in the 37-degree heat of the incubator so that the embryo can develop. Alread

https://www.stemcellcenter.lu.se/article/eggs-can-help-us-understand-neuroblastoma - 2025-02-21

What makes blood stem cells transform? Regulation of RNA splicing may be an answer.

By press [at] med [dot] lu [dot] se (Faculty of Medicine) - published 24 March 2023 Cristian Bellodi and Maciej Cieśla. Photo: Helena Fritz Researchers at Lund Stem Cell Center and Lund University's Faculty of Medicine have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published i

https://www.stemcellcenter.lu.se/article/what-makes-blood-stem-cells-transform-regulation-rna-splicing-may-be-answer - 2025-02-21

From vision to reality: 20 years of cutting-edge research at Lund Stem Cell Center

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 13 April 2023 In 2023, the Lund Stem Cell Center turns 20 years old. This will be celebrated with a conference attended by some of the world's leading stem cell researchers. Image: iStock/Maksim Tkachenko For two decades, researchers at Lund University's strategic research area, Lund Stem Cell Center, have focused on d

https://www.stemcellcenter.lu.se/article/vision-reality-20-years-cutting-edge-research-lund-stem-cell-center - 2025-02-21

Interdisciplinary Teams Unite to Develop Patient-Specific Disease Models

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 28 April 2023 Researchers from Lund Stem Cell Center are coming together with colleagues across Lund University to shape the future of healthcare. A new University-wide seed funding initiative seeking to support emerging research topics that benefit society will see interdisciplinary teams of neuroscience, medicine, an

https://www.stemcellcenter.lu.se/article/interdisciplinary-teams-lund-university-unite-develop-patient-tailored-disease-models - 2025-02-21

Decoding the Inner Workings of a Blood Stem Cell-Boosting Molecule

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 24 May 2023 A model of a proteasome, a protein complex which degrades unneeded or damaged proteins. Image from: Getty Images. A recent study conducted by researchers at Lund University's Lund Stem Cell Center, and published in the Journal of Biological Chemistry, has unraveled the intricate inner workings of UM171—a mo

https://www.stemcellcenter.lu.se/article/decoding-inner-workings-blood-stem-cell-boosting-molecule - 2025-02-21

New Study Reveals Astrocytes' Role in Frontotemporal Dementia

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 31 May 2023 An image of co-cultures with neuronal projections in purple and astrocytes in green. Image credit: Isaac Canals. Lund Stem Cell Center researchers have published a new study that reveals the role of astrocytes in the development of frontotemporal dementia (FTD). Their findings, now in the journal Brain Comm

https://www.stemcellcenter.lu.se/article/new-study-reveals-astrocytes-role-frontotemporal-dementia - 2025-02-21

Investigating a cell replacement therapy for Parkinson's Disease: a Ph.D. Interview with Fredrik Nilsson

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 8 June 2023 Fredrik Nilsson successfully defended his Ph.D. thesis on May 10, 2023. For the last four years, Fredrik has explored the use of patient-specific cells in cell replacement therapy for Parkinson's disease to identify strategies to safeguard these transplanted cells from disease-related degeneration. In this

https://www.stemcellcenter.lu.se/article/investigating-cell-replacement-therapy-parkinsons-disease-phd-interview-fredrik-nilsson - 2025-02-21